Oncopeptides will host a webcaston Monday, January 27th 2020 were CEO Jakob Lindberg will present and explain melflufen’s mechanism of action. The presentation will be available below just before the start of the webcast. Conference call for investors, analysts and the media, Monday, January 27th 2020, at 11 (CET)

Data från Oncopeptides kliniska studier, HORIZON och ANCHOR, där melflufen utvärderas i RRMM, har accepterats för presentation vid AACR årsmöte.

2020-11-19 Oncopeptides AB (publ) was formed in 2000 to develop anti-cancer drugs based on research by some of Sweden’s leading cancer researchers and cancer research institutions. Development of melflufen The development of melflufen, stems from work originally undertaken by Dr Joachim Gullbo at Uppsala University, Sweden, on a molecule initially known as ‘J1’. 2020-06-17 20 hours ago 2 days ago Our clinical studies. Oncopeptides. Accessed October 19, 2020. https://oncopeptides.se/en/section/our-clinical-trials/ 2. Safety and efficacy of melflufen and dexamethasone in relapsed and/or relapsed-refractory multiple myeloma patients.

2020-06-17 20 hours ago 2 days ago Our clinical studies. Oncopeptides. Accessed October 19, 2020. https://oncopeptides.se/en/section/our-clinical-trials/ 2. Safety and efficacy of melflufen and dexamethasone in relapsed and/or relapsed-refractory multiple myeloma patients.

Melflufen is a novel peptide-drug conjugate that rapidly delivers a cytotoxic payload into tumor cells. It has emerged as a potential new multiple myeloma treatment, particularly for late-stage forms of the disease. Here we describe the rationale and design of OCEAN (NCT03151811), a randomized, head …

The … STOCKHOLM — April 16, 2021 — Oncopeptides AB (publ) (Nasdaq Stockholm: ONCO), a global biotech company focused on the development of therapies for difficult-to-treat hematological diseases, today announces that the Company has submitted an application to the European Medicines Agency, EMA, for conditional marketing authorization of melflufen (melphalan flufenamide) in the EU, based on the STOCKHOLM — May 14, 2020 — Oncopeptides AB (Nasdaq Stockholm: ONCO) announces today that data from the pivotal phase 2 study HORIZON, and additional clinical and preclinical data that further evaluate the therapeutic peptide-drug conjugate platform, have been accepted by the European Hematology Association (EHA). The abstracts are now published online. Melflufen (melphalan … 2021-02-27 2020-05-15 1 day ago It is an important milestone for Oncopeptides, and a major step in making melflufen available for patients with multiple myeloma, who desperately need new treatment options,” says Marty J Duvall, CEO of Oncopeptides.

Oncopeptides startar ett Expanded Access Program i USA med melflufen i trippelklassrefraktärt multipelt myelom tor, okt 01, 2020 08:00 CET. STOCKHOLM — 1 oktober 2020 — Oncopeptides AB (publ) (Nasdaq Stockholm: ONCO) tillkännager idag att bolagets Expanded Access Program sEAPort formellt öppnas för lämpade patienter i USA.

Updated August 24, 2020. The US Food and Drug Administration (FDA) has granted priority review for the company’s New Drug Application seeking approval of melflufen in combination with dexamethasone for the treatment of adult patients with multiple myeloma whose disease is refractory to at least one proteasome inhibitor, one immunomodulatory agent and one anti-CD-38 monoclonal antibody. 2 dagar sedan · Oncopeptides har lämnat in en ansökan om villkorat godkännande i EU för sin behandling melflufen mot cancer i benmärgen. Ansökan är baserad på en fas II-studie, som utvärderar melflufen (INN melphalan flufenamid) tillsammans med dexametason för behandling av multipelt myelom.

Bolaget fokuserar på utvecklingen av produktkandidaten melflufen, ett nytt peptidlänkat cancerläkemedel som snabbt levererar ett alkylerande cellgift till tumörceller. 2 dagar sedan · Läkemedelsbolaget Oncopeptides har lämnat in en ansökan om villkorat marknadsgodkännande för melflufen i EU vid behandling av en form av blodcancerformen multipelt myelom. Det framgår av ett pressmeddelande. About Oncopeptides Oncopeptides is a pharmaceutical company focused on the development of targeted therapies for difficult-to-treat hematological diseases.
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Conference call for investors, analysts and the media, Monday, January 27th 2020, at 11 (CET) Oncopeptides Announces New Clinical and Preclinical Melflufen Data at the Upcoming European Hematology Association Meeting PRESS RELEASE PR Newswire May. 14, 2020, 03:13 PM About Oncopeptides Oncopeptides is a pharmaceutical company focused on the development of targeted therapies for difficult-to-treat hematological diseases. The company is focusing on the development of the lead product candidate melflufen, a first-in-class peptide-drug conjugate that rapidly delivers a cytotoxic payload into tumor cells. Oncopeptides has one U.S. FDA approved product, PEPAXTO® (melphalan flufenamide), known during clinical development as melflufen.

2020-10-23 · Oncopeptides, which specializes in developing targeted therapies for difficult-to-treat hematological diseases, also announced it has entered into a loan agreement with the European Investment Bank (EIB), which will enable the company to access a loan of €40 million (around $47 million) to support melflufen’s clinical development, and its transition to a global biopharmaceutical company. As an R&D stage pharmaceutical company focused on developing drugs for the treatment of cancer, Oncopeptides has developed a product called Melflufen for the treatment of MM. As a lipophilic peptide conjugated alkylator, Melflufen rapidly delivers a highly cytotoxic payload into myeloma cells through peptidase activity.
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The US Food and Drug Administration (FDA) has granted priority review for the company’s New Drug Application seeking approval of melflufen in combination with dexamethasone for the treatment of adult patients with multiple myeloma whose disease is refractory to at least one proteasome inhibitor, one immunomodulatory agent and one anti-CD-38 monoclonal antibody.

Svarsfrekvensen för melflufen i patientpopulationen med 17p-deletion från fas Safety and efficacy of melflufen and dexamethasone in relapsed and/or relapsed-refractory multiple myeloma patients. ClinicalTrials.gov Identifier: NCT01897714.

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26 Mar 2020 Oncopeptides AB remains on track for an NDA filing in the second quarter for its peptide-drug conjugate, melflufen, in relapsed refractory

Updated August 24, 2020. Accessed October 19, 2020. 2020-10-01 2 days ago Melflufen is the first drug candidate coming out of the company´s proprietary Peptide Drug Conjugate platform, PDC. Oncopeptides has recently submitted an Investigational New Drug application for its second drug candidate from this technology platform, OPD5. About Oncopeptides Oncopeptides is a pharmaceutical company focused on the development of targeted therapies for difficult-to-treat hematological diseases. The lead product candidate melflufen, is a first in class peptide-drug conjugate that targets aminopeptidases and releases alkylating agents into … 2020-04-06 2020-09-04 Oncopeptides Announces New Clinical and Preclinical Melflufen Data at the Upcoming European Hematology Association Meeting PRESS RELEASE PR Newswire May. 14, 2020, 03:13 PM Melphalan flufenamide, sold under the brand name Pepaxto, is an anticancer medication used to treat multiple myeloma.. The most common adverse reactions include fatigue, nausea, diarrhea, pyrexia and respiratory tract infection. Melphalan flufenamide is a peptidase enhanced cytotoxic (PEnC) that exerts a targeted delivery of melphalan in cells with high expression of aminopeptidases, such as 2020-11-04 For more information on melflufen contact the Medical Information department directly by phone at 1-866-522-8894 or by email at medinfo@oncopeptides.com.

26 Feb 2021 PEPAXTO® (melphalan flufenamide, also known as melflufen) is the first anticancer peptide-drug conjugate for patients with relapsed or

The abstracts are now published online. Melflufen (melphalan … 2021-02-27 2020-05-15 1 day ago It is an important milestone for Oncopeptides, and a major step in making melflufen available for patients with multiple myeloma, who desperately need new treatment options,” says Marty J Duvall, CEO of Oncopeptides. 2020-11-19 Oncopeptides AB (publ) was formed in 2000 to develop anti-cancer drugs based on research by some of Sweden’s leading cancer researchers and cancer research institutions. Development of melflufen The development of melflufen, stems from work originally undertaken by Dr Joachim Gullbo at Uppsala University, Sweden, on a molecule initially known as ‘J1’. 2020-06-17 20 hours ago 2 days ago Our clinical studies. Oncopeptides. Accessed October 19, 2020.

Det säger Oncopeptides vd Marty J Duvall under måndagens kapitalmarknadsdag. Strategin i Europa är att liksom i USA sköta lanseringen av melflufen vid behandling av en form av blodcancerformen multipelt myelom på egen hand ("go it alone"). I Japan kommer Oncopeptides troligen att vilja gå till marknaden tillsammans med en partner. 2020-11-19 · Oncopeptides vd Marty J Duvall uppger att bolaget står redo för en lansering av melflufen i USA vid behandling av en form av blodcancerformen multipelt myelom. Det framgår av vd-ordet i delårsrapporten. STOCKHOLM (Nyhetsbyrån Direkt) Läkemedelsbolaget Oncopeptides har fått ett villkorat godkännande av den amerikanska läkemedelsmyndigheten FDA i USA för melflufen under varumärkesnamnet Pepaxto. Godkännandet omfattar behandling av blodcancerformen multipelt myelom, där patienter genomgått åtminstone fyra behandlingslinjer.