2014-10-30

8 Oct 2020 A novel single‐dose BC that can provide an extended period of safe myocardial ischemic arrest was developed by Matte and del Nido and was

2019-12-24 · Conclusions: It is safe to use del Nido cardioplegia in coronary artery bypass grafting combined with heart valve replacement in adults, which can reduce the frequency of cardioplegia infusion and simplify the surgical procedure. The trend of troponin concentration suggests that del Nido cardioplegia has a better myocardial protective effect. Blood cardioplegia (BC), which is the mixture of the subject's oxygenated blood (80%) and a crystalloid solution (20%), is the most widely used cardioplegia type [ 1]. The del Nido solution was formulated by researchers from the University of Pittsburgh (Pittsburgh, PA, USA) in the early 1990s [ 5].

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It can be used as a single dose and it is a reasonable tool do decrease cardioplegic interventions. Del Nido (DN) cardioplegic solution (CPS) has been widely used during pediatric cardiac surgery. However, its use in the field of adult cardiac surgery is not popular yet. We evaluated efficacy of DN cardioplegia in adult cardiac surgical patients.Fifty-three Asanguinous, Del Nido cardioplegia was used for myocardial protection.

The del Nido cardioplegia solution was essentially developed for use in paediatric cardiac surgery as myocardial protection in the immature heart was considered to be different than in the adult heart [ 2, 3 ]. It was subsequently tried in adult cardiac surgery, with good results.

It has been used for pediatric cardiac surgery in Boston’s Children Hospital since 1994 and, since 2003, it has been successfully used for adult cardiac surgery as well [8]. 2016-12-30 Del Nido vs. Buckberg Cardioplegia in Adult Isolated Valve Surgery Stephanie L Mick, Michael Robich, Catherine Torma, Annmarie Fatula, Patrick Grady, A. Marc Gillinov, Edward Soltesz, Douglas R Johnston, Joseph F Sabik, III Cleveland Clinic, Cleveland, OH. OBJECTIVES: Del Nido cardioplegia is a non-glucose-based solution given as a single dose that provides up to 180 minutes of cardiac quiescence. Matte GS, del Nido PJ. History and use of del Nido cardioplegia solution at Boston Children's Hospital.

Commonly referred to as ‘‘del Nido … The del Nido cardioplegia is a crystalloid solution (Plasma-Lyte A, lidocaine, magnesium sulfate, potassium chloride, mannitol, sodium bicarbonate), mixed with blood in a 1:4 ratio (blood/crystalloid). Lidocaine is believed to be the primary component, as it increases the myocyte refractory period and reduces sodium and calcium influx.
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Buel ST , Striker CW , O'Brien JE J Extra Corpor Technol , … Purpose:del Nido cardioplegia solution (CPS) has been successfully used for myocardial protection in the pediatric population.

Conclusions: It is safe to use del Nido cardioplegia in coronary artery bypass grafting combined with heart valve replacement in adults, which can reduce the frequency of cardioplegia infusion and simplify the surgical procedure.
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2015-11-01 · Del Nido cardioplegia is routinely used in clinical practice both in paediatric and adult population in high volume centres. It could be a safe, effective and cheap myocardial protection strategy of universal implementation in cardiac surgery. Additional prospective studies are needed to confirm these data.

Cardioplegia Induction Plasmalyte / Tromethamine High Potassiu. Del Nido cardioplegia use in an adult, reoperative aortic valve population offers equivalent postoperative outcomes when compared with whole blood cardioplegia.

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Objectives: The del Nido cardioplegia solution has been used extensively in congenital heart surgery for more than 20 years and more recently for adults. This randomized controlled trial examined whether expanding this technique to adult cardiac surgery confers benefits in surgical workflow and clinical outcome compared with blood-based cardioplegia.

However, there is a scarcity of data supporting its safety in adults undergoing complex cardiac surgery, such as aortic root repair. del Nido cardioplegia is a newer solution getting popular worldwide, whereas in Nepal, St. Thomas cardioplegia solution is conventionally used. There is no national recommendation on cardioplegia solutions supported by evidences from Nepalese studies. Del Nido cardioplegia Del Nido cardioplegia was developed by Pedro Del Nido and his team at the University of Pittsburgh in 1990s.

18 Sep 2019 Del Nido cardioplegia was initially used in pediatric patients and has been expanding into adult cardiac centers over the last decade. It can be

The trend of troponin concentration suggests that del Nido cardioplegia has a better myocardial protective effect. Del Nido (DN) cardioplegia solution provides a depolarized hyperkalemic arrest lasting up to 60 minutes, and the addition of lidocaine may limit intracellular calcium influx. A novel formula for inducing cardioplegia was introduced in congenital heart surgery in 1995.5,6 Led by Pedro del Nido, MD, researchers from the University of Pittsburgh patented this formula as a single dose of a modiﬁed depolarizing solution. Commonly referred to as ‘‘del Nido solution,’’ this blood and crystalloid Del Nido cardioplegia was initially used in pediatric patients and has been expanding into adult cardiac centers over the last decade. It can be used as a single dose and it is a reasonable tool do decrease cardioplegic interventions.

The del Nido cardioplegia is a crystalloid solution (Plasma-Lyte A, lidocaine, magnesium sulfate, potassium chloride, mannitol, sodium bicarbonate), mixed with blood in a 1:4 ratio (blood/crystalloid). Lidocaine is believed to be the primary component, as it increases the myocyte refractory period and reduces sodium and calcium influx.